Cargando…

Poor prognosis in cholangiocarcinoma patients with low FBXW7 expression is improved by chemotherapy

The tumor suppressor FBXW7 has been demonstrated to degrade several oncoproteins, including c-Myc. Although low FBXW7 expression levels are suggested to be a poor prognostic factor in a number of types of solid tumor, the role of FBXW7 in chemosensitivity is controversial. The purpose of the present...

Descripción completa

Detalles Bibliográficos
Autores principales: Ishii, Norihiro, Araki, Kenichiro, Yokobori, Takehiko, Watanabe, Akira, Tsukagoshi, Mariko, Kubo, Norio, Suzuki, Hideki, Saito, Fumiyoshi, Altan, Bolag, Hosouchi, Yasuo, Shirabe, Ken, Kuwano, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431321/
https://www.ncbi.nlm.nih.gov/pubmed/28521468
http://dx.doi.org/10.3892/ol.2017.5946