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Poor prognosis in cholangiocarcinoma patients with low FBXW7 expression is improved by chemotherapy
The tumor suppressor FBXW7 has been demonstrated to degrade several oncoproteins, including c-Myc. Although low FBXW7 expression levels are suggested to be a poor prognostic factor in a number of types of solid tumor, the role of FBXW7 in chemosensitivity is controversial. The purpose of the present...
Autores principales: | Ishii, Norihiro, Araki, Kenichiro, Yokobori, Takehiko, Watanabe, Akira, Tsukagoshi, Mariko, Kubo, Norio, Suzuki, Hideki, Saito, Fumiyoshi, Altan, Bolag, Hosouchi, Yasuo, Shirabe, Ken, Kuwano, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431321/ https://www.ncbi.nlm.nih.gov/pubmed/28521468 http://dx.doi.org/10.3892/ol.2017.5946 |
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