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The Light Intermediate Chain 2 Subpopulation of Dynein Regulates Mitotic Spindle Orientation

Cytoplasmic dynein 1 is a multi-protein intracellular motor essential for mediating several mitotic functions, including the establishment of proper spindle orientation. The functional relevance and mechanistic distinctions between two discrete dynein subpopulations distinguished only by Light Inter...

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Detalles Bibliográficos
Autores principales: Mahale, Sagar, Kumar, Megha, Sharma, Amit, Babu, Aswini, Ranjan, Shashi, Sachidanandan, Chetana, Mylavarapu, Sivaram V. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431351/
https://www.ncbi.nlm.nih.gov/pubmed/28003657
http://dx.doi.org/10.1038/s41598-016-0030-3