Cargando…
The Light Intermediate Chain 2 Subpopulation of Dynein Regulates Mitotic Spindle Orientation
Cytoplasmic dynein 1 is a multi-protein intracellular motor essential for mediating several mitotic functions, including the establishment of proper spindle orientation. The functional relevance and mechanistic distinctions between two discrete dynein subpopulations distinguished only by Light Inter...
Autores principales: | Mahale, Sagar, Kumar, Megha, Sharma, Amit, Babu, Aswini, Ranjan, Shashi, Sachidanandan, Chetana, Mylavarapu, Sivaram V. S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431351/ https://www.ncbi.nlm.nih.gov/pubmed/28003657 http://dx.doi.org/10.1038/s41598-016-0030-3 |
Ejemplares similares
-
Dynein Light Intermediate Chain 2 Facilitates the Metaphase to Anaphase Transition by Inactivating the Spindle Assembly Checkpoint
por: Mahale, Sagar P., et al.
Publicado: (2016) -
Phosphorylation and Pin1 binding to the LIC1 subunit selectively regulate mitotic dynein functions
por: Kumari, Amrita, et al.
Publicado: (2021) -
The dynein adaptor Hook2 plays essential roles in mitotic progression and cytokinesis
por: Dwivedi, Devashish, et al.
Publicado: (2019) -
Functional interaction between dynein light chain and intermediate chain is required for mitotic spindle positioning
por: Stuchell-Brereton, Melissa D., et al.
Publicado: (2011) -
Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly
por: Chan, Ying Wai, et al.
Publicado: (2009)