Cardioprotective effects of Cu((II))ATSM in human vascular smooth muscle cells and cardiomyocytes mediated by Nrf2 and DJ-1

Cu((II))ATSM was developed as a hypoxia sensitive positron emission tomography agent. Recent reports have highlighted the neuroprotective properties of Cu((II))ATSM, yet there are no reports that it confers cardioprotection. We demonstrate that Cu((II))ATSM activates the redox-sensitive transcriptio...

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Detalles Bibliográficos
Autores principales: Srivastava, Salil, Blower, Philip J., Aubdool, Aisah A., Hider, Robert C., Mann, Giovanni E., Siow, Richard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431352/
https://www.ncbi.nlm.nih.gov/pubmed/28442712
http://dx.doi.org/10.1038/s41598-016-0012-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431352/
https://www.ncbi.nlm.nih.gov/pubmed/28442712
http://dx.doi.org/10.1038/s41598-016-0012-5

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