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Phosphorylation and acetylation modifications of FOXO3a: Independently or synergistically?

Forkhead box class O 3a (FOXO3a) is a transcription factor that has emerged as being a tumor suppressor and longevity factor. The precise regulation of FOXO3a transactivation of target genes is achieved via post-translational modifications (PTMs) and specific protein-protein interactions. The multip...

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Detalles Bibliográficos
Autores principales: Wang, Xianwang, Hu, Shujuan, Liu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431355/
https://www.ncbi.nlm.nih.gov/pubmed/28521392
http://dx.doi.org/10.3892/ol.2017.5851