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High-Resolution Morphological Approach to Analyse Elastic Laminae Injuries of the Ascending Aorta in a Murine Model of Marfan Syndrome

In Marfan syndrome, the tunica media is disrupted, which leads to the formation of ascending aortic aneurysms. Marfan aortic samples are histologically characterized by the fragmentation of elastic laminae. However, conventional histological techniques using transverse sections provide limited infor...

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Detalles Bibliográficos
Autores principales: López-Guimet, Júlia, Andilla, Jordi, Loza-Alvarez, Pablo, Egea, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431420/
https://www.ncbi.nlm.nih.gov/pubmed/28473723
http://dx.doi.org/10.1038/s41598-017-01620-8