Notochordal and nucleus pulposus marker expression is maintained by sub-populations of adult human nucleus pulposus cells through aging and degeneration

The nucleus pulposus (NP) of the intervertebral disc (IVD) demonstrates substantial changes in cell and matrix composition with both ageing and degeneration. While recent transcriptomic profiling studies have helped define human NP cell phenotype, it remains unclear how expression of these markers i...

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Detalles Bibliográficos
Autores principales: Richardson, Stephen M., Ludwinski, Francesca E., Gnanalingham, Kanna K., Atkinson, Ross A., Freemont, Anthony J., Hoyland, Judith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431421/
https://www.ncbi.nlm.nih.gov/pubmed/28473691
http://dx.doi.org/10.1038/s41598-017-01567-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431421/
https://www.ncbi.nlm.nih.gov/pubmed/28473691
http://dx.doi.org/10.1038/s41598-017-01567-w

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