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DNA methylation and Transcriptome Changes Associated with Cisplatin Resistance in Ovarian Cancer
High-grade serous ovarian cancer is the most common ovarian cancer type. Although the combination of surgery and platinum-taxane chemotherapy provide an effective treatment, drug resistance frequently occurs leading to poor outcome. In order to clarify the molecular mechanisms of drug resistance, th...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431431/ https://www.ncbi.nlm.nih.gov/pubmed/28473707 http://dx.doi.org/10.1038/s41598-017-01624-4 |