Cryptolepine inhibits melanoma cell growth through coordinated changes in mitochondrial biogenesis, dynamics and metabolic tumor suppressor AMPKα1/2-LKB1

Dysregulated mitochondrial dynamics and biogenesis have been associated with various pathological conditions including cancers. Here, we assessed the therapeutic effect of cryptolepine, a pharmacologically active alkaloid derived from the roots of Cryptolepis sanguinolenta, on melanoma cell growth....

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Detalles Bibliográficos
Autores principales: Pal, Harish C., Prasad, Ram, Katiyar, Santosh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431443/
https://www.ncbi.nlm.nih.gov/pubmed/28473727
http://dx.doi.org/10.1038/s41598-017-01659-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431443/
https://www.ncbi.nlm.nih.gov/pubmed/28473727
http://dx.doi.org/10.1038/s41598-017-01659-7

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