Tyrosine kinase inhibitors of Ripk2 attenuate bacterial cell wall-mediated lipolysis, inflammation and dysglycemia

Inflammation underpins aspects of insulin resistance and dysglycemia. Microbiota-derived cell wall components such as muropeptides or endotoxin can trigger changes in host immunity and metabolism. Specific peptidoglycan motifs promote metabolic tissue inflammation, lipolysis and insulin resistance v...

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Detalles Bibliográficos
Autores principales: Duggan, Brittany M., Foley, Kevin P., Henriksbo, Brandyn D., Cavallari, Joseph F., Tamrakar, Akhilesh K., Schertzer, Jonathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431485/
https://www.ncbi.nlm.nih.gov/pubmed/28484277
http://dx.doi.org/10.1038/s41598-017-01822-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431485/
https://www.ncbi.nlm.nih.gov/pubmed/28484277
http://dx.doi.org/10.1038/s41598-017-01822-0

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