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Predicting influenza antigenicity from Hemagglutintin sequence data based on a joint random forest method

Timely identification of emerging antigenic variants is critical to influenza vaccine design. The accuracy of a sequence-based antigenic prediction method relies on the choice of amino acids substitution matrices. In this study, we first compared a comprehensive 95 substitution matrices reflecting v...

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Detalles Bibliográficos
Autores principales: Yao, Yuhua, Li, Xianhong, Liao, Bo, Huang, Li, He, Pingan, Wang, Fayou, Yang, Jiasheng, Sun, Hailiang, Zhao, Yulong, Yang, Jialiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431489/
https://www.ncbi.nlm.nih.gov/pubmed/28484283
http://dx.doi.org/10.1038/s41598-017-01699-z