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Predicting influenza antigenicity from Hemagglutintin sequence data based on a joint random forest method
Timely identification of emerging antigenic variants is critical to influenza vaccine design. The accuracy of a sequence-based antigenic prediction method relies on the choice of amino acids substitution matrices. In this study, we first compared a comprehensive 95 substitution matrices reflecting v...
Autores principales: | Yao, Yuhua, Li, Xianhong, Liao, Bo, Huang, Li, He, Pingan, Wang, Fayou, Yang, Jiasheng, Sun, Hailiang, Zhao, Yulong, Yang, Jialiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431489/ https://www.ncbi.nlm.nih.gov/pubmed/28484283 http://dx.doi.org/10.1038/s41598-017-01699-z |
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