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Wnt inhibitory factor 1 (WIF1) methylation and its association with clinical prognosis in patients with chondrosarcoma

Chondrosarcoma (CS) is a rare cancer, but it is the second most common primary malignant bone tumor and highly resistant to conventional chemotherapy and radiotherapy. Aberrant DNA methylation in the promoter CpG island of Wnt inhibitory factor 1 (WIF1) has been observed in different cancers. Howeve...

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Detalles Bibliográficos
Autores principales: Liu, Pei, Shen, Jacson K., Hornicek, Francis J., Liu, Fuyun, Duan, Zhenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431504/
https://www.ncbi.nlm.nih.gov/pubmed/28484252
http://dx.doi.org/10.1038/s41598-017-01763-8