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Identification of Tp0751 (Pallilysin) as a Treponema pallidum Vascular Adhesin by Heterologous Expression in the Lyme disease Spirochete

Treponema pallidum subsp. pallidum, the causative agent of syphilis, is a highly invasive spirochete pathogen that uses the vasculature to disseminate throughout the body. Identification of bacterial factors promoting dissemination is crucial for syphilis vaccine development. An important step in di...

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Detalles Bibliográficos
Autores principales: Kao, Wei-Chien Andrew, Pětrošová, Helena, Ebady, Rhodaba, Lithgow, Karen V., Rojas, Pablo, Zhang, Yang, Kim, Yae-Eun, Kim, Yae-Ram, Odisho, Tanya, Gupta, Nupur, Moter, Annette, Cameron, Caroline E., Moriarty, Tara J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431505/
https://www.ncbi.nlm.nih.gov/pubmed/28484210
http://dx.doi.org/10.1038/s41598-017-01589-4