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Role of GATA binding protein 4 (GATA4) in the regulation of tooth development via GNAI3

Transcription factor GATA4 regulates cardiac and osteoblast differentiation. However, its role in tooth development is not clear. Therefore, we generated Wnt1-Cre;GATA4 (fl/fl) mice, with conditional inactivation of the GATA4 gene in the dental papilla mesenchymal cells. Phenotypic analysis showed s...

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Detalles Bibliográficos
Autores principales: Guo, Shuyu, Zhang, Yuxin, Zhou, Tingting, Wang, Dongyue, Weng, Yajuan, Wang, Lin, Ma, Junqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431507/
https://www.ncbi.nlm.nih.gov/pubmed/28484278
http://dx.doi.org/10.1038/s41598-017-01689-1