Expression proteomics study to determine metallodrug targets and optimal drug combinations

The emerging technique termed functional identification of target by expression proteomics (FITExP) has been shown to identify the key protein targets of anti-cancer drugs. Here, we use this approach to elucidate the proteins involved in the mechanism of action of two ruthenium(II)-based anti-cancer...

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Detalles Bibliográficos
Autores principales: Lee, Ronald F. S., Chernobrovkin, Alexey, Rutishauser, Dorothea, Allardyce, Claire S., Hacker, David, Johnsson, Kai, Zubarev, Roman A., Dyson, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431558/
https://www.ncbi.nlm.nih.gov/pubmed/28484215
http://dx.doi.org/10.1038/s41598-017-01643-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431558/
https://www.ncbi.nlm.nih.gov/pubmed/28484215
http://dx.doi.org/10.1038/s41598-017-01643-1

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