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GIRK2 splice variants and neuronal G protein-gated K(+) channels: implications for channel function and behavior

Many neurotransmitters directly inhibit neurons by activating G protein-gated inwardly rectifying K(+) (GIRK) channels, thereby moderating the influence of excitatory input on neuronal excitability. While most neuronal GIRK channels are formed by GIRK1 and GIRK2 subunits, distinct GIRK2 isoforms gen...

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Detalles Bibliográficos
Autores principales: Marron Fernandez de Velasco, Ezequiel, Zhang, Lei, N. Vo, Baovi, Tipps, Megan, Farris, Shannon, Xia, Zhilian, Anderson, Allison, Carlblom, Nicholas, Weaver, C. David, Dudek, Serena M., Wickman, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431628/
https://www.ncbi.nlm.nih.gov/pubmed/28487514
http://dx.doi.org/10.1038/s41598-017-01820-2