Retinal Degeneration In A Mouse Model Of CLN5 Disease Is Associated With Compromised Autophagy

The Finnish variant of late infantile neuronal ceroid lipofuscinosis (CLN5 disease) belongs to a family of neuronal ceroid lipofuscinosis (NCLs) diseases. Vision loss is among the first clinical signs in childhood forms of NCLs. Mutations in CLN5 underlie CLN5 disease. The aim of this study was to c...

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Detalles Bibliográficos
Autores principales: Leinonen, Henri, Keksa-Goldsteine, Velta, Ragauskas, Symantas, Kohlmann, Philip, Singh, Yajuvinder, Savchenko, Ekaterina, Puranen, Jooseppi, Malm, Tarja, Kalesnykas, Giedrius, Koistinaho, Jari, Tanila, Heikki, Kanninen, Katja M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431647/
https://www.ncbi.nlm.nih.gov/pubmed/28487519
http://dx.doi.org/10.1038/s41598-017-01716-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431647/
https://www.ncbi.nlm.nih.gov/pubmed/28487519
http://dx.doi.org/10.1038/s41598-017-01716-1

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