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Improved thrombolytic effect with focused ultrasound and neuroprotective agent against acute carotid artery thrombosis in rat

Combination therapy with focused ultrasound (FUS) and a neuroprotective agent, BNG-1, was examined in an acute carotid thrombotic occlusion model using LED irradiation in rat to improve the thrombolytic effect of rt-PA. Seven treatment groups included (A) intravenous bolus injection of 0.45 mg/kg rt...

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Detalles Bibliográficos
Autores principales: Lee, Tsong-Hai, Yeh, Jih-Chao, Tsai, Chih-Hung, Yang, Jen-Tsung, Lou, Shyh-Liang, Seak, Chen-June, Wang, Chao-Yung, Wei, Kuo-Chen, Liu, Hao-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431649/
https://www.ncbi.nlm.nih.gov/pubmed/28487554
http://dx.doi.org/10.1038/s41598-017-01769-2