Protein Phosphatase 2A (PP2A) Regulates EG5 to Control Mitotic Progression

EG5 (KIF11) is a member of the kinesin-like protein family involved in centrosome separation and bipolar spindle formation. When a cell enters mitosis, CDK1 phosphorylates EG5 at Thr926 and promotes EG5 localization on the mitotic spindle which drives bipolar spindle formation. EG5 provides power fo...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Zhang, Zhong, Liang, Hui, Zhao, Xuyang, Liang, Ling, Wang, Guangxi, Yang, Jingyi, Jin, Yan, McNutt, Michael A., Yin, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431654/
https://www.ncbi.nlm.nih.gov/pubmed/28487562
http://dx.doi.org/10.1038/s41598-017-01915-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431654/
https://www.ncbi.nlm.nih.gov/pubmed/28487562
http://dx.doi.org/10.1038/s41598-017-01915-w

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