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In vivo and in vitro ageing results in accumulation of de novo copy number variations in bulls
We have identified de novo copy number variations (CNVs) generated in bulls as they age. Blood samples from eight bulls were collected and SNP arrayed in a prospective design over 30 months allowing us to differentiate de novo CNVs from constant CNVs that are present throughout the sampling period....
Autores principales: | Revay, Tamas, Oluwole, Olutobi, Kroetsch, Tom, King, W. Allan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431667/ https://www.ncbi.nlm.nih.gov/pubmed/28487564 http://dx.doi.org/10.1038/s41598-017-01793-2 |
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