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Artificial disulfide-rich peptide scaffolds with precisely defined disulfide patterns and a minimized number of isomers

Disulfide-rich peptides are emerging as potential templates for drug design applications. However, the synthesis and reengineering of disulfide-rich peptides are challenging, owing to the complexity of the oxidative folding process involving a number of diverse isomeric structures. Novel disulfide-r...

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Detalles Bibliográficos
Autores principales: Zheng, Yiwu, Li, Zhuoru, Ren, Jing, Liu, Weidong, Wu, Yaqi, Zhao, Yibing, Wu, Chuanliu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431680/
https://www.ncbi.nlm.nih.gov/pubmed/28553486
http://dx.doi.org/10.1039/c6sc05710a