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Polyethylene glycol–poly(ε-benzyloxycarbonyl-l-lysine)-conjugated VEGF siRNA for antiangiogenic gene therapy in hepatocellular carcinoma

A polyethylene glycol–poly(ε-benzyloxycarbonyl-l-lysine) (PEG-SS-PLL) block copolymer based on a disulfide-linked, novel biodegradable catiomer bearing a PEG-sheddable shell was developed to avoid “PEG dilemma” in nanoparticle intracellular tracking of PEG-PLL where PEG was nondegradable. However, P...

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Detalles Bibliográficos
Autores principales: Wang, Gangmin, Gao, XiaoLong, Gu, GuoJun, Shao, ZhiHong, Li, MingHua, Wang, PeiJun, Yang, JianRong, Cai, XiaoJun, Li, YongYong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431695/
https://www.ncbi.nlm.nih.gov/pubmed/28533682
http://dx.doi.org/10.2147/IJN.S131078