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Effect of epigallocatechin-3-gallate, major ingredient of green tea, on the pharmacokinetics of rosuvastatin in healthy volunteers

Previous in vitro studies have demonstrated the inhibitory effect of green tea on drug transporters. Because rosuvastatin, a lipid-lowering drug widely used for the prevention of cardiovascular events, is a substrate for many drug transporters, there is a possibility that there is interaction betwee...

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Detalles Bibliográficos
Autores principales: Kim, Tae-Eun, Ha, Na, Kim, Yunjeong, Kim, Hyunsook, Lee, Jae Wook, Jeon, Ji-Young, Kim, Min-Gul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431696/
https://www.ncbi.nlm.nih.gov/pubmed/28533679
http://dx.doi.org/10.2147/DDDT.S130050