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The molecular basis of thin filament activation: from single molecule to muscle

For muscles to effectively power locomotion, trillions of myosin molecules must rapidly attach and detach from the actin thin filament. This is accomplished by precise regulation of the availability of the myosin binding sites on actin (i.e. activation). Both calcium (Ca(++)) and myosin binding cont...

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Detalles Bibliográficos
Autores principales: Longyear, Thomas, Walcott, Sam, Debold, Edward P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431769/
https://www.ncbi.nlm.nih.gov/pubmed/28500282
http://dx.doi.org/10.1038/s41598-017-01604-8