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A-Kinase Anchoring Protein 79/150 Scaffolds Transient Receptor Potential A 1 Phosphorylation and Sensitization by Metabotropic Glutamate Receptor Activation

Mechanical pain serves as a base clinical symptom for many of the world’s most debilitating syndromes. Ion channels expressed by peripheral sensory neurons largely contribute to mechanical hypersensitivity. Transient Receptor Potential A 1 (TRPA1) is a ligand-gated ion channel that contributes to in...

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Detalles Bibliográficos
Autores principales: Brackley, Allison Doyle, Gomez, Ruben, Guerrero, Kristi A., Akopian, Armen N., Glucksman, Marc J., Du, Junhui, Carlton, Susan M., Jeske, Nathaniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431798/
https://www.ncbi.nlm.nih.gov/pubmed/28500286
http://dx.doi.org/10.1038/s41598-017-01999-4