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Folate Metabolism Regulates Oligodendrocyte Survival and Differentiation by Modulating AMPKα Activity
Folate, an essential micronutrient, is a critical cofactor in one-carbon metabolism for many cellular pathways including DNA synthesis, metabolism and maintenance. Folate deficiency has been associated with an increased risk of neurological disease, cancer and cognitive dysfunction. Dihydrofolate re...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431811/ https://www.ncbi.nlm.nih.gov/pubmed/28496133 http://dx.doi.org/10.1038/s41598-017-01732-1 |