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Folate Metabolism Regulates Oligodendrocyte Survival and Differentiation by Modulating AMPKα Activity

Folate, an essential micronutrient, is a critical cofactor in one-carbon metabolism for many cellular pathways including DNA synthesis, metabolism and maintenance. Folate deficiency has been associated with an increased risk of neurological disease, cancer and cognitive dysfunction. Dihydrofolate re...

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Detalles Bibliográficos
Autores principales: Weng, Qinjie, Wang, Jiajia, Wang, Jiaying, Tan, Biqin, Wang, Jing, Wang, Haibo, Zheng, Tao, Lu, Q. Richard, Yang, Bo, He, Qiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431811/
https://www.ncbi.nlm.nih.gov/pubmed/28496133
http://dx.doi.org/10.1038/s41598-017-01732-1