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Neuregulin 1 improves complex 2-mediated mitochondrial respiration in skeletal muscle of healthy and diabetic mice

It has been reported that neuregulin1 (NRG1) improves glucose tolerance in healthy and diabetic rodents. In vitro studies also suggest that NRG1 regulates myocyte oxidative capacity. To confirm this observation in vivo, we evaluated the effect on mitochondrial function of an 8-week treatment with NR...

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Detalles Bibliográficos
Autores principales: Ennequin, Gaël, Capel, Frederic, Caillaud, Kevin, Chavanelle, Vivien, Etienne, Monique, Teixeira, Allison, Li, Xinyan, Boisseau, Nathalie, Sirvent, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431817/
https://www.ncbi.nlm.nih.gov/pubmed/28496106
http://dx.doi.org/10.1038/s41598-017-02029-z