ALOX5 exhibits anti-tumor and drug-sensitizing effects in MLL-rearranged leukemia

MLL-rearranged acute myeloid leukemia (AML) remains a fatal disease with a high rate of relapse and therapeutic failure due to chemotherapy resistance. In analysis of our Affymetrix microarray profiling and chromatin immunoprecipitation (ChIP) assays, we found that ALOX5 is especially down-regulated...

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Detalles Bibliográficos
Autores principales: Wang, Yungui, Skibbe, Jennifer R., Hu, Chao, Dong, Lei, Ferchen, Kyle, Su, Rui, Li, Chenying, Huang, Hao, Weng, Hengyou, Huang, Huilin, Qin, Xi, Jin, Jie, Chen, Jianjun, Jiang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431828/
https://www.ncbi.nlm.nih.gov/pubmed/28500307
http://dx.doi.org/10.1038/s41598-017-01913-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431828/
https://www.ncbi.nlm.nih.gov/pubmed/28500307
http://dx.doi.org/10.1038/s41598-017-01913-y

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