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Fine-tune regulation of carboxypeptidase N1 controls vascular patterning during zebrafish development

Vascular development is regulated by complicated signals and molecules in vertebrates. In this study, we characterized a novel function of carboxypeptidase N1 (Cpn1) in the vasculature. We show that cpn1 mRNA is expressed in developing vessels. The knockdown of cpn1 by morpholino injection impairs t...

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Detalles Bibliográficos
Autores principales: Wu, Ting-Yun, Wang, Yi-Shan, Song, Yi-Chun, Chen, Zih-Ying, Chen, Yi-Ting, Chiu, Chien-Chih, Wu, Chang-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431830/
https://www.ncbi.nlm.nih.gov/pubmed/28500283
http://dx.doi.org/10.1038/s41598-017-01976-x