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Ethylenation of aldehydes to 3-propanal, propanol and propanoic acid derivatives

Methodology has been developed for the synthesis of 3-propanaldehydes through a five-step process in 11–67% yield from aldehydes. Aldehydes were reacted with Meldrum’s acid through a Knoevenagel condensation to give materials that upon reduction with sodium borohydride and subsequent hydrolysis deca...

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Detalles Bibliográficos
Autores principales: Payne, Daniel T., Zhao, Yiming, Fossey, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431831/
https://www.ncbi.nlm.nih.gov/pubmed/28496208
http://dx.doi.org/10.1038/s41598-017-01950-7