A comparative multi-parametric in vitro model identifies the power of test conditions to predict the fibrotic tendency of a biomaterial

Despite growing effort to advance materials towards a low fibrotic progression, all implants elicit adverse tissue responses. Pre-clinical biomaterial assessment relies on animals testing, which can be complemented by in vitro tests to address the Russell and Burch’s 3R aspect of reducing animal bur...

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Detalles Bibliográficos
Autores principales: Jannasch, Maren, Gaetzner, Sabine, Weigel, Tobias, Walles, Heike, Schmitz, Tobias, Hansmann, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431855/
https://www.ncbi.nlm.nih.gov/pubmed/28490729
http://dx.doi.org/10.1038/s41598-017-01584-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431855/
https://www.ncbi.nlm.nih.gov/pubmed/28490729
http://dx.doi.org/10.1038/s41598-017-01584-9

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