Cargando…

A comparative multi-parametric in vitro model identifies the power of test conditions to predict the fibrotic tendency of a biomaterial

Despite growing effort to advance materials towards a low fibrotic progression, all implants elicit adverse tissue responses. Pre-clinical biomaterial assessment relies on animals testing, which can be complemented by in vitro tests to address the Russell and Burch’s 3R aspect of reducing animal bur...

Descripción completa

Detalles Bibliográficos
Autores principales: Jannasch, Maren, Gaetzner, Sabine, Weigel, Tobias, Walles, Heike, Schmitz, Tobias, Hansmann, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431855/
https://www.ncbi.nlm.nih.gov/pubmed/28490729
http://dx.doi.org/10.1038/s41598-017-01584-9

Ejemplares similares