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CD163(+)CD204(+) tumor-associated macrophages contribute to T cell regulation via interleukin-10 and PD-L1 production in oral squamous cell carcinoma

Tumor-associated macrophages (TAMs) promote cancer cell proliferation, invasion, and metastasis by producing various mediators. Although preclinical studies demonstrated that TAMs preferentially express CD163 and CD204, the TAM subsets in oral squamous cell carcinoma (OSCC) remain unknown. In this s...

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Detalles Bibliográficos
Autores principales: Kubota, Keigo, Moriyama, Masafumi, Furukawa, Sachiko, Rafiul, Haque A. S. M., Maruse, Yasuyuki, Jinno, Teppei, Tanaka, Akihiko, Ohta, Miho, Ishiguro, Noriko, Yamauchi, Masaaki, Sakamoto, Mizuki, Maehara, Takashi, Hayashida, Jun-Nosuke, Kawano, Shintaro, Kiyoshima, Tamotsu, Nakamura, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431876/
https://www.ncbi.nlm.nih.gov/pubmed/28496107
http://dx.doi.org/10.1038/s41598-017-01661-z