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Genomic RNA folding mediates assembly of human parechovirus

Assembly of the major viral pathogens of the Picornaviridae family is poorly understood. Human parechovirus 1 is an example of such viruses that contains 60 short regions of ordered RNA density making identical contacts with the protein shell. We show here via a combination of RNA-based systematic e...

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Detalles Bibliográficos
Autores principales: Shakeel, Shabih, Dykeman, Eric C., White, Simon J., Ora, Ari, Cockburn, Joseph J.B., Butcher, Sarah J., Stockley, Peter G., Twarock, Reidun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431903/
https://www.ncbi.nlm.nih.gov/pubmed/28232749
http://dx.doi.org/10.1038/s41467-016-0011-z