Alpha7 nicotinic acetylcholine receptor agonist promotes retinal ganglion cell function via modulating GABAergic presynaptic activity in a chronic glaucomatous model

Alpha-7 nicotinic acetylcholine receptor (α7-nAChR) agonists can prevent glutamate-induced excitotoxicity in cultured retinal ganglion cells (RGCs). However, the neuroprotective effects and the mechanism of action of PNU-282987, an α7-nAChR agonist, in a chronic in vivo rat glaucoma model are poorly...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Xujiao, Cheng, Yun, Zhang, Rong, Li, Gang, Yang, Boqi, Zhang, Shenghai, Wu, Jihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431927/
https://www.ncbi.nlm.nih.gov/pubmed/28496108
http://dx.doi.org/10.1038/s41598-017-02092-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431927/
https://www.ncbi.nlm.nih.gov/pubmed/28496108
http://dx.doi.org/10.1038/s41598-017-02092-6

Ejemplares similares