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Combined treatment with Metformin and 2-deoxy glucose induces detachment of viable MDA-MB-231 breast cancer cells in vitro

Triple naegative breast cancer has an increased rate of distant metastasis and consequently poor prognosis. To metastasize, breast cancer cells must detach from the main tumour mass and resist anoikis, a programmed cell death induced by lack of cell-extracellular matrix communication. Although cance...

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Detalles Bibliográficos
Autores principales: Bizjak, Maruša, Malavašič, Petra, Dolinar, Klemen, Pohar, Jelka, Pirkmajer, Sergej, Pavlin, Mojca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431940/
https://www.ncbi.nlm.nih.gov/pubmed/28496098
http://dx.doi.org/10.1038/s41598-017-01801-5