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Combined treatment with Metformin and 2-deoxy glucose induces detachment of viable MDA-MB-231 breast cancer cells in vitro
Triple naegative breast cancer has an increased rate of distant metastasis and consequently poor prognosis. To metastasize, breast cancer cells must detach from the main tumour mass and resist anoikis, a programmed cell death induced by lack of cell-extracellular matrix communication. Although cance...
Autores principales: | Bizjak, Maruša, Malavašič, Petra, Dolinar, Klemen, Pohar, Jelka, Pirkmajer, Sergej, Pavlin, Mojca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431940/ https://www.ncbi.nlm.nih.gov/pubmed/28496098 http://dx.doi.org/10.1038/s41598-017-01801-5 |
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