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Extracellular Vesicles Carry HIV Env and Facilitate Hiv Infection of Human Lymphoid Tissue

Cells productively infected with HIV-1 release virions along with extracellular vesicles (EVs) whose biogenesis, size, and physical properties resemble those of retroviruses. Here, we found that a significant number of EVs (exosomes) released by HIV-1 infected cells carry gp120 (Env), a viral protei...

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Detalles Bibliográficos
Autores principales: Arakelyan, Anush, Fitzgerald, Wendy, Zicari, Sonia, Vanpouille, Christophe, Margolis, Leonid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431974/
https://www.ncbi.nlm.nih.gov/pubmed/28490736
http://dx.doi.org/10.1038/s41598-017-01739-8