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A Systems Genetics Approach Identified GPD1L and its Molecular Mechanism for Obesity in Human Adipose Tissue

To explore novel molecular mechanisms underlying obesity, we applied a systems genetics framework to integrate risk genetic loci from the largest body mass index (BMI) genome-wide association studies (GWAS) meta-analysis with mRNA and microRNA profiling in adipose tissue from 200 subjects. One modul...

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Detalles Bibliográficos
Autores principales: He, Hao, Sun, Dianjianyi, Zeng, Yong, Wang, Ruifeng, Zhu, Wei, Cao, Shaolong, Bray, George A., Chen, Wei, Shen, Hui, Sacks, Frank M., Qi, Lu, Deng, Hong-wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431993/
https://www.ncbi.nlm.nih.gov/pubmed/28496128
http://dx.doi.org/10.1038/s41598-017-01517-6