Dendritic cells provide a therapeutic target for synthetic small molecule analogues of the parasitic worm product, ES-62

ES-62, a glycoprotein secreted by the parasitic filarial nematode Acanthocheilonema viteae, subverts host immune responses towards anti-inflammatory phenotypes by virtue of covalently attached phosphorylcholine (PC). The PC dictates that ES-62 exhibits protection in murine models of inflammatory dis...

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Detalles Bibliográficos
Autores principales: Lumb, Felicity E., Doonan, James, Bell, Kara S., Pineda, Miguel A., Corbet, Marlene, Suckling, Colin J., Harnett, Margaret M., Harnett, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431997/
https://www.ncbi.nlm.nih.gov/pubmed/28490801
http://dx.doi.org/10.1038/s41598-017-01651-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431997/
https://www.ncbi.nlm.nih.gov/pubmed/28490801
http://dx.doi.org/10.1038/s41598-017-01651-1

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