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Dendritic cells provide a therapeutic target for synthetic small molecule analogues of the parasitic worm product, ES-62
ES-62, a glycoprotein secreted by the parasitic filarial nematode Acanthocheilonema viteae, subverts host immune responses towards anti-inflammatory phenotypes by virtue of covalently attached phosphorylcholine (PC). The PC dictates that ES-62 exhibits protection in murine models of inflammatory dis...
Autores principales: | Lumb, Felicity E., Doonan, James, Bell, Kara S., Pineda, Miguel A., Corbet, Marlene, Suckling, Colin J., Harnett, Margaret M., Harnett, William |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431997/ https://www.ncbi.nlm.nih.gov/pubmed/28490801 http://dx.doi.org/10.1038/s41598-017-01651-1 |
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