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Tumor suppressor menin is required for subunit-specific nAChR α5 transcription and nAChR-dependent presynaptic facilitation in cultured mouse hippocampal neurons

In the central nervous system (CNS), cholinergic transmission induces synaptic plasticity that is required for learning and memory. However, our understanding of the development and maintenance of cholinergic circuits is limited, as the factors regulating the expression and clustering of neuronal ni...

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Detalles Bibliográficos
Autores principales: Getz, Angela M., Xu, Fenglian, Visser, Frank, Persson, Roger, Syed, Naweed I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432004/
https://www.ncbi.nlm.nih.gov/pubmed/28496137
http://dx.doi.org/10.1038/s41598-017-01825-x