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Near-atomic structure of Japanese encephalitis virus reveals critical determinants of virulence and stability

Although several different flaviviruses may cause encephalitis, Japanese encephalitis virus is the most significant, being responsible for thousands of deaths each year in Asia. The structural and molecular basis of this encephalitis is not fully understood. Here, we report the cryo-electron microsc...

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Detalles Bibliográficos
Autores principales: Wang, Xiangxi, Li, Shi-Hua, Zhu, Ling, Nian, Qing-Gong, Yuan, Shuai, Gao, Qiang, Hu, Zhongyu, Ye, Qing, Li, Xiao-Feng, Xie, Dong-Yang, Shaw, Neil, Wang, Junzhi, Walter, Thomas S., Huiskonen, Juha T., Fry, Elizabeth E., Qin, Cheng-Feng, Stuart, David I., Rao, Zihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432033/
https://www.ncbi.nlm.nih.gov/pubmed/28446752
http://dx.doi.org/10.1038/s41467-017-00024-6