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IFN-γ fails to overcome inhibition of selected macrophage activation events in response to pathogenic mycobacteria

According to most models of mycobacterial infection, inhibition of the pro-inflammatory macrophage immune responses contributes to the persistence of bacteria. Mycobacterium avium subsp. paratuberculosis (MAP) is a highly successful pathogen in cattle and sheep and is also implicated as the causativ...

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Detalles Bibliográficos
Autores principales: Thirunavukkarasu, Shyamala, Plain, Karren M., Purdie, Auriol C., Whittington, Richard J., de Silva, Kumudika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432162/
https://www.ncbi.nlm.nih.gov/pubmed/28505170
http://dx.doi.org/10.1371/journal.pone.0176400