Cargando…
Epistatic interaction between the lipase-encoding genes Pnpla2 and Lipe causes liposarcoma in mice
Liposarcoma is an often fatal cancer of fat cells. Mechanisms of liposarcoma development are incompletely understood. The cleavage of fatty acids from acylglycerols (lipolysis) has been implicated in cancer. We generated mice with adipose tissue deficiency of two major enzymes of lipolysis, adipose...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432192/ https://www.ncbi.nlm.nih.gov/pubmed/28459858 http://dx.doi.org/10.1371/journal.pgen.1006716 |