Shank is a dose-dependent regulator of Ca(v)1 calcium current and CREB target expression

Shank is a post-synaptic scaffolding protein that has many binding partners. Shank mutations and copy number variations (CNVs) are linked to several psychiatric disorders, and to synaptic and behavioral defects in mice. It is not known which Shank binding partners are responsible for these defects....

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Detalles Bibliográficos
Autores principales: Pym, Edward, Sasidharan, Nikhil, Thompson-Peer, Katherine L, Simon, David J, Anselmo, Anthony, Sadreyev, Ruslan, Hall, Qi, Nurrish, Stephen, Kaplan, Joshua M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432211/
https://www.ncbi.nlm.nih.gov/pubmed/28477407
http://dx.doi.org/10.7554/eLife.18931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432211/
https://www.ncbi.nlm.nih.gov/pubmed/28477407
http://dx.doi.org/10.7554/eLife.18931

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