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Shank is a dose-dependent regulator of Ca(v)1 calcium current and CREB target expression
Shank is a post-synaptic scaffolding protein that has many binding partners. Shank mutations and copy number variations (CNVs) are linked to several psychiatric disorders, and to synaptic and behavioral defects in mice. It is not known which Shank binding partners are responsible for these defects....
Autores principales: | Pym, Edward, Sasidharan, Nikhil, Thompson-Peer, Katherine L, Simon, David J, Anselmo, Anthony, Sadreyev, Ruslan, Hall, Qi, Nurrish, Stephen, Kaplan, Joshua M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432211/ https://www.ncbi.nlm.nih.gov/pubmed/28477407 http://dx.doi.org/10.7554/eLife.18931 |
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